⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409266 | 1.00 | — | — | |
| Sulfamate SCHEMBL28304617 | 0.77 | — | — | |
| SCHEMBL18254464 | 0.76 | — | — | |
| SCHEMBL20792925 | 0.76 | — | — | |
| SCHEMBL18474671 | 0.76 | — | — | |
| SCHEMBL18254250 | 0.76 | — | — | |
| SCHEMBL43258 | 0.75 | — | — | |
| SCHEMBL21766997 | 0.74 | — | — | |
| SCHEMBL2219991 | 0.72 | — | — | |
| SCHEMBL8083316 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040345-A | KIF18A inhibitory activity small molecule compound, and pharmaceutical composition and application thereof | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2025-05-27 | — | — | CN | claimed |
| WO-2025049798-A1 | SYSTEMS, METHODS, AND DEVICES FOR DESTRUCTION OF PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) AND FOR REACTIVATING SPENT ACTIVATED CARBON | 6K INC. (US) | 2025-03-06 | — | — | WO | claimed |
| CN-115920065-A | Ligand capable of targeting asialoglycoprotein receptor, conjugate and application thereof | 南方科技大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115295893-A | Aqueous zinc ion battery low-temperature electrolyte and additive thereof | 北京理工大学长三角研究院(嘉兴) | 2022-11-04 | — | — | CN | claimed |
| EP-1430120-A4 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | ALCON INC (CH) | 2007-06-20 | — | — | EP | claimed |
| EP-1430120-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | Alcon, Inc. (CH) | 2004-06-23 | — | — | EP | claimed |
| WO-2003027275-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2003-04-03 | — | — | WO | claimed |
| US-12637445-B2 | KIF18A inhibitors | AMGEN INC. (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4676475-A1 | HIV-1P ROTEASE INHIBITORS AND USES THEREOF | Purdue Research Foundation (US) | 2026-01-14 | — | — | EP | disclosed |
| EP-4289481-B1 | METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-B]PYRAN-8-OL | PURDUE RESEARCH FOUNDATION (US) | 2025-09-17 | — | — | EP | disclosed |
| US-12365691-B2 | Method of synthesizing (3S,3AR,5R,7AS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-ol | PURDUE RESEARCH FOUNDATION (US) | 2025-07-22 | — | — | US | disclosed |
| CN-120040345-A | KIF18A inhibitory activity small molecule compound, and pharmaceutical composition and application thereof | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2025-05-27 | — | — | CN | disclosed |
| WO-2025067239-A1 | KINESIN KIF18A INHIBITOR, AND APPLICATION THEREOF | 上海湃隆生物科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-1996028464-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-19 | — | — | WO | disclosed |
| WO-1996022275-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1996022275-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |
| US-4256597-A | DETERGENT AND PHOTOINITIATOR COMPRISING A PORPHINE OR MONO, DI, OR TRIAZO PORPHINE, OR PHTHALOCYANINE COMPOUND; WATER SOLUBILITY; STAIN REMOVAL | THE PROCTER & GAMBLE COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4255273-A | COMPRISING A WATER-SOLUBLE PHOTOACTIVATOR AND A CATIONIC SUBSTANCE | THE PROCTER & GAMBLE COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4240920-A | A SURFACTANT, A PEROXY BLEACH AND A PORPHINE BLEACH | THE PROCTER & GAMBLE COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| EP-0003149-A2 | Composition containing a photoactivator for improved washing and bleaching of fabrics | THE PROCTER & GAMBLE COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |