⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160213 | 1.00 | — | — | |
| Sulfamate SCHEMBL28304617 | 0.77 | — | — | |
| SCHEMBL18254464 | 0.76 | — | — | |
| SCHEMBL20792925 | 0.76 | — | — | |
| SCHEMBL18474671 | 0.76 | — | — | |
| SCHEMBL18254250 | 0.76 | — | — | |
| SCHEMBL43258 | 0.75 | — | — | |
| SCHEMBL21766997 | 0.74 | — | — | |
| SCHEMBL2219991 | 0.72 | — | — | |
| SCHEMBL8083316 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289481-B1 | METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-B]PYRAN-8-OL | PURDUE RESEARCH FOUNDATION (US) | 2025-09-17 | — | — | EP | disclosed |
| US-12365691-B2 | Method of synthesizing (3S,3AR,5R,7AS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-ol | PURDUE RESEARCH FOUNDATION (US) | 2025-07-22 | — | — | US | disclosed |
| US-20230399338-A1 | METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-b]PYRAN-8-OL | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-12-14 | — | — | US | disclosed |
| EP-4289481-A1 | METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-B]PYRAN-8-OL | Purdue Research Foundation (US) | 2023-12-13 | — | — | EP | disclosed |
| US-9309213-B2 | C-3 substituted bicyclooctane based HIV protease inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140148508-A1 | C-3 SUBSTITUTED BICYCLOOCTANE BASED HIV PROTEASE INHIBITORS | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) | 2014-05-29 | — | — | US | disclosed |
| WO-2013009844-A2 | C-3 SUBSTITUTED BICYCLOOCTANE BASED HIV PROTEASE INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2013-01-17 | — | — | WO | disclosed |
| EP-1709037-B1 | HIV PROTEASE INHIBITING SULFONAMIDES | ABBOTT LAB (US) | 2009-12-23 | — | — | EP | disclosed |