Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427391 | 0.90 | POLB (0.50) | POLBALDH1A1SMN1; SMN2MMEL1MEN1 | |
| SCHEMBL17427393 | 0.90 | POLB (0.49) | POLBALDH1A1MMEL1HPGDLMNA | |
| SCHEMBL17427401 | 0.88 | POLB (0.42) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17427408 | 0.87 | POLB (0.41) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL17427407 | 0.87 | POLB (0.49) | POLBALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL17430377 | 0.86 | POLB (0.40) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL17427384 | 0.86 | BRD9 (0.48) | POLBALDH1A1SMN1; SMN2LMNAGRM5 | |
| SCHEMBL17222514 | 0.85 | POLB (0.51) | POLBALDH1A1SMN1; SMN2MMEL1MEN1 | |
| SCHEMBL17430275 | 0.84 | IKBKE (0.40) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17427457 | 0.84 | POLB (0.48) | POLBALDH1A1MMEL1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135654-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | POLB 4093/4885ALDH1A1 79/4885SMN1; SMN2 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.