⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172300 | 0.72 | — | — | |
| SCHEMBL24533820 | 0.72 | — | — | |
| SCHEMBL29387730 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL2650256 | 0.70 | — | — | |
| SCHEMBL1145239 | 0.70 | — | — | |
| SCHEMBL15564628 | 0.68 | — | — | |
| SCHEMBL12332236 | 0.68 | — | — | |
| SCHEMBL171912 | 0.68 | — | — | |
| SCHEMBL73460 | 0.68 | — | — | |
| SCHEMBL451566 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230002-A1 | NLRP3 INFLAMMASOME INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20230200210-A1 | ONCN QUADRIDENTATE LIGAND-CONTAINING PLATINUM COMPLEX AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODE | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230200210-A1 | ONCN QUADRIDENTATE LIGAND-CONTAINING PLATINUM COMPLEX AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODE | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| EP-3189052-B1 | CAMKII INHIBITORS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2021-11-03 | — | — | EP | disclosed |
| EP-2964221-B1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME (US) | 2017-12-06 | — | — | EP | disclosed |
| CN-107331892-A | A kind of electrolyte, positive pole and preparation method thereof and a kind of lithium ion battery | 比亚迪股份有限公司 | 2017-11-07 | — | — | CN | disclosed |
| EP-2964220-B1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME (US) | 2017-10-04 | — | — | EP | disclosed |
| EP-3070081-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | Gilead Sciences, Inc. (US) | 2016-09-21 | — | — | EP | disclosed |
| EP-2788336-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |
| WO-2015026683-A1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2015-02-26 | — | — | WO | disclosed |
| EP-2801570-A1 | Inhibitors of beta-secretase | Vitae Pharmaceuticals, Inc. (US) | 2014-11-12 | — | — | EP | disclosed |
| EP-2786995-A1 | Azaindoles useful as inhibitors of JAK and other protein kinases | Vertex Pharmaceuticals Incorporated (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2014134776-A1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014137725-A1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014137728-A1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2014-09-12 | — | — | WO | disclosed |