SCHEMBL172300

SCHEMBL172300

Clc1ccnc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387730 1.00
Hydrochloric Acid SCHEMBL2650256 0.97
Pyrimidine SCHEMBL28152588 0.86 TRPA1 (0.41)
SCHEMBL1273717 0.86 LOXL2 (0.41)
Methylamine SCHEMBL26629712 0.86 LOX (0.45)
Pyrazole SCHEMBL28218646 0.79 IDO1 (0.41)
SCHEMBL827247 0.77 CCR1 (0.48)
SCHEMBL4027001 0.77 IDO1 (0.55)
SCHEMBL1145239 0.74
SCHEMBL3500189 0.72 MAP4K4 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115477639-A Multi-substituted pyrimidine compound with FGFR1 as target spot, and preparation method and application thereof 温州医科大学 2022-12-16 CN claimed
CN-113754579-A Preparation method of pyridine derivative 正大天晴药业集团股份有限公司 2021-12-07 CN claimed
CN-111440144-A Method for industrially producing bromopyrazolic acid through micro-channel 山东华科化工有限公司 2020-07-24 CN claimed
CN-107778255-B A kind of Diarylmiazines HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2019-10-25 CN claimed
CN-106750301-B Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2019-03-22 CN claimed
CN-108864052-A A kind of synthesis and application of the fluorescence probe for GC33-3-1 antibody with specific recognition 福建医科大学 2018-11-23 CN claimed
CN-108440398-A A kind of process for separation and purification of 2- chloropyridines rectifying bottom liquid 安徽国星生物化学有限公司 2018-08-24 CN claimed
CN-108350034-A Antimicrobial polymyxin derived compounds 莫纳什大学 2018-07-31 CN claimed
CN-106188053-B A kind of electron transport material, preparation method and applications 中节能万润股份有限公司 2017-11-07 CN claimed
CN-106750301-A Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2017-05-31 CN claimed
CN-106117125-A The synthetic method of medical material 2,4-difluoro pyridine 无锡乾浩生物医药有限公司 2016-11-16 CN claimed
CN-105949244-A Two green-light iridium phosphorescence complexes and synthesis method thereof 昆明贵金属研究所 2016-09-21 CN claimed
CN-105949245-A Yellow light emitting iridium phosphorescence coordination compound and method for preparing same 昆明贵金属研究所 2016-09-21 CN claimed
CN-105753773-A A synthetic method of a medicine raw material 2-chloro-4-fluoropyridine 无锡乾浩生物医药有限公司 2016-07-13 CN claimed
CN-101429205-B Process for producing 3,4-enedioxy thiophene Zhejiang puluo debang pharmaceutical co ltd 2011-05-25 CN claimed
CN-101429205-A Process for producing 3,4-enedioxy thiophene ZHEJIANG PULUO DEBANG PHARMACE (CN) 2009-05-13 CN claimed
CN-1181058-C Process for preparing pyridylphenylureas 四川省兰月科技开发公司 2004-12-22 CN claimed
CN-1453269-A Process for preparing pyridylphenylureas LANYUE SCI TECH DEV CO LTD SIC (CN) 2003-11-05 CN claimed
EP-0220080-B1 COMPOSITIONS BASED ON PHTHALONITRILE-TERMINATED POLYARYLOXY PYRIDINE OLIGOMERS, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF POLYARYLOXY PYRIDINE COPHTHALOCYANINE LATTICES AND LATTICES OBTAINED CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1990-02-07 EP claimed
US-4764578-A Compositions of polyaryloxypyridine oligomers with phthalonitrile end groups, their preparation and use for manufacturing polyaryloxypyridine co-phthalocyanine lattices CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-08-16 US claimed