SCHEMBL1603293

SCHEMBL1603293

CC(CN1CCOCC1)OCCN1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.44
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX12 P18054 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
HTR2A P28223 1/20 0.39
MAPK1 P28482 1/20 0.39
SCN1A P35498 1/20 0.39
HTR2B P41595 1/20 0.39
KCNH2 Q12809 1/20 0.39
SCN2A Q99250 1/20 0.39
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19928688 0.85 ALDH1A1 (0.44) USP2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL10454916 0.85 MAPK1 (0.37) ALDH1A1NPC1TDP1KDM4EMEN1
SCHEMBL10455897 0.85 EBP (0.37) USP2ALDH1A1NPC1L3MBTL1TDP1
SCHEMBL10454470 0.83 DRD1 (0.39) ALDH1A1NPC1L3MBTL1TDP1MEN1
SCHEMBL10456041 0.83 NPC1 (0.35) USP2ALDH1A1NPC1L3MBTL1KDM4E
SCHEMBL9136935 0.82 MEN1 (0.43) USP2ALDH1A1TDP1KDM4EMEN1
SCHEMBL4104702 0.82 MEN1 (0.43) USP2ALDH1A1TDP1KDM4EMEN1
SCHEMBL8328670 0.81 USP2 (0.47) USP2ALDH1A1NPC1L3MBTL1KDM4E
SCHEMBL10455794 0.80 MEN1 (0.34) USP2ALDH1A1TDP1KDM4EMEN1
SCHEMBL11122383 0.80 NPC1 (0.42) USP2ALDH1A1NPC1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607899-A2 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-27 EP claimed
US-5002047-A Supporting or cushioning body part with pad of open-celled foam impregnated with water curable polyurethane MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-26 US claimed
EP-0226287-A1 Catalysts for the curing of a water-curable isocyanate-functional prepolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-24 EP claimed
US-20110082406-A1 SAFETY CAST EBI, LLC (US) 2011-04-07 US disclosed
US-7837637-B2 Safety cast EBI, LLC (US) 2010-11-23 US disclosed
US-20070255189-A1 Safety cast EBI, L.P. (US) 2007-11-01 US disclosed
WO-2007120855-A2 SAFETY CAST EBI, L.P. (US) 2007-10-25 WO disclosed
EP-1368191-B1 COMPOSITE ARTICLES REINFORCED WITH HIGHLY ORIENTED MICROFIBERS 3M INNOVATIVE PROPERTIES CO (US) 2006-04-26 EP disclosed
US-7014803-B2 Composite articles reinforced with highly oriented microfibers 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-21 US disclosed
US-6991610-B2 Orthopedic fixture ALCARE CO., LTD. (JP) 2006-01-31 US disclosed
EP-0978266-B1 Physical position-retaining device for individuals ALCARE CO LTD (JP) 2005-02-23 EP disclosed
EP-0306327-A2 Orthotic pads and methods MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4788339-A HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-29 US disclosed
US-4774937-A PRELUBRICATED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-10-04 US disclosed
EP-0279612-A1 Orthopedic splinting articles and methods MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-08-24 EP disclosed
US-4705840-A Catalysts for the curing of a water-curable isocyanate-functional prepolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-10 US disclosed
US-4683877-A Orthopedic casting article and method MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-08-04 US disclosed
EP-0226287-A1 Catalysts for the curing of a water-curable isocyanate-functional prepolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-24 EP disclosed
US-4667661-A ORTHOPEDIC CASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-26 US disclosed
EP-0221669-A1 Curable resin coated sheet having reduced tack MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-13 EP disclosed