SCHEMBL1603294

SCHEMBL1603294

CC(COCCN1CCOCC1)N1CCOCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
SYK P43405 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
HTR2A P28223 1/20 0.41
SCN1A P35498 1/20 0.41
HTR2B P41595 1/20 0.41
KCNH2 Q12809 1/20 0.41
SCN2A Q99250 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
SCN3A Q9NY46 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 1/20 0.40
KEAP1 Q14145 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455635 0.84 DRD1 (0.40) TSHRSYKCYP2D6ALDH1A1HRH3
SCHEMBL2608938 0.84 ALDH1A1 (0.47) TSHRALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL8980000 0.83 KMT2A (0.44) TSHRALDH1A1USP2LMNAMEN1
SCHEMBL23471085 0.81 SMN1; SMN2 (0.46) TSHRALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL11128458 0.81 HSD17B10 (0.44) TSHRALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL18871964 0.77 KMT2A (0.46) TSHRSYKCYP2D6ALDH1A1HTR2A
SCHEMBL10456034 0.77 HRH3 (0.34) HRH3MEN1KMT2A
SCHEMBL2608937 0.77 ALDH1A1 (0.49) TSHRCYP2D6ALDH1A1MAPK1CYP1A2
SCHEMBL24352759 0.77 USP2 (0.41) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL26940059 0.77 ALDH1A1 (0.45) TSHRALDH1A1MAPK1CYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110082406-A1 SAFETY CAST EBI, LLC (US) 2011-04-07 US disclosed
US-7837637-B2 Safety cast EBI, LLC (US) 2010-11-23 US disclosed
US-20070255189-A1 Safety cast EBI, L.P. (US) 2007-11-01 US disclosed
WO-2007120855-A2 SAFETY CAST EBI, L.P. (US) 2007-10-25 WO disclosed
US-20040171975-A1 Casting aid and methods of forming casts BIOMET, INC. 2004-09-02 US disclosed
US-6673727-B2 SUBSTRATE IMPREGNATED WITH A WATER-CURABLE RESIN COMPRISING AN AROMATIC POLYISOCYANATE AND A POLYOL, WITH GIVEN LEVEL OF FREE ISOCYANATE (NCO); KITS EBI, L.P. 2004-01-06 US disclosed
US-20020160684-A1 Orthopedic casts with controlled flexibility BREG, INC. 2002-10-31 US disclosed
US-20020147420-A1 Casting aid and methods of forming casts EBI, L.P. 2002-10-10 US disclosed
EP-1015348-A1 EASY OPEN PACKAGE AND METHOD OF MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-07-05 EP disclosed
EP-1006961-A2 NOVEL CASTING TAPE ARTICLE AND METHOD FOR MOLDING CASTS Ebi Medical Systems Inc. (US) 2000-06-14 EP disclosed
WO-1992018550-A1 CURABLE RESINS WITH SOLID SUPPORTED ANTIFOAMING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-29 WO disclosed
EP-0214852-B1 PERFLUOROAMINOETHERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-28 EP disclosed
EP-0486020-A2 Luminescent water-curable materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-20 EP disclosed
US-5049670-A Pour point MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-17 US disclosed
EP-0226287-B1 CATALYSTS FOR THE CURING OF A WATER-CURABLE ISOCYANATE-FUNCTIONAL PREPOLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-07-11 EP disclosed
US-4929725-A NONFLAMMABLE, HYDRAULIC FLUIDS MOORE GEORGE G I (US) 1990-05-29 US disclosed
US-4871845-A 2,2*-DIMORPHOVINYLDIALKYL ETHER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-03 US disclosed
US-4788339-A HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-29 US disclosed
US-4705840-A Catalysts for the curing of a water-curable isocyanate-functional prepolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-10 US disclosed
EP-0226287-A1 Catalysts for the curing of a water-curable isocyanate-functional prepolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-24 EP disclosed