Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.47 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034162 | 1.00 | POLB (0.55) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL11883457 | 0.85 | THRB (0.59) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL8649033 | 0.85 | CYP1A2 (0.56) | CYP2D6KMT2ATDP1MAPTGAA | |
| SCHEMBL8649035 | 0.85 | CYP1A2 (0.56) | CYP2D6KMT2ATDP1MAPTGAA | |
| SCHEMBL8961472 | 0.83 | SUMO2 (0.53) | KMT2ATDP1MAPTGAAMAPK1 | |
| SCHEMBL3009727 | 0.80 | CYP1A2 (0.77) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL3009730 | 0.80 | CYP1A2 (0.77) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL7089862 | 0.78 | MPL (0.60) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL135509 | 0.78 | CYP1A2 (0.75) | POLBCYP2D6KMT2ATDP1MAPT | |
| SCHEMBL9343019 | 0.78 | CYP1A2 (0.75) | POLBCYP2D6KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140261517-A1 | COMPOSITIONS AND METHODS FOR TREATING KERATIN BASED FIBERS | COOLWAY INC. (US) | 2014-09-18 | — | — | US | disclosed |