Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | PPARD | Q03181 | 9/20 | 0.62 |
| ▸ | PPARA | Q07869 | 9/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.62 |
| ▸ | FABP4 | P15090 | 4/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604033 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1603606 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119017 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119181 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1603608 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119014 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119177 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119019 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1604031 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1119179 | 1.00 | PPARG (0.62) | PPARGPPARDPPARAPTPN1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663444-B2 | Heteroatom containing substituted fatty acids | COMPLEXA, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2017-04-27 | — | — | US | disclosed |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2483233-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | Miller, Raymond A. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041639-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | MILLER RAYMOND A (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PPARG 14/4885PPARD 39/4885PPARA 15/4885 |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PPARG 14/4885PPARD 39/4885PPARA 15/4885 |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PPARG 14/4885PPARD 39/4885PPARA 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.