Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16036634 | 1.00 | ABCB1 (0.40) | ABCB1CYP3A4TPMTHTTNPSR1 | |
| SCHEMBL20052551 | 0.90 | ABCB1 (0.41) | ABCB1CYP3A4 | |
| SCHEMBL2682569 | 0.88 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL16035449 | 0.88 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL2682853 | 0.88 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL17424965 | 0.83 | ABCB1 (0.41) | ABCB1CYP3A4TPMTHTTNPSR1 | |
| SCHEMBL20383955 | 0.79 | TPMT (0.39) | ABCB1CYP3A4TPMTHTT | |
| SCHEMBL27354891 | 0.79 | TPMT (0.39) | ABCB1CYP3A4TPMTHTT | |
| SCHEMBL8581806 | 0.74 | TPMT (0.45) | ABCB1TPMTNPSR1 | |
| SCHEMBL20460261 | 0.74 | TPMT (0.38) | ABCB1CYP3A4TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851119-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2020-05-21 | — | — | US | disclosed |
| CN-107406373-B | Boron-containing diacylhydrazine compounds | 英特瑞克斯顿股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| EP-3194359-B1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORP (US) | 2020-04-08 | — | — | EP | disclosed |
| US-10570158-B2 | Boron-containing diacylhydrazine compounds | INTREXON CORPORATION (US) | 2020-02-25 | — | — | US | disclosed |
| US-10464951-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180201628-A1 | Boron-Containing Diacylhydrazine Compounds | INTREXON CORP (US) | 2018-07-19 | — | — | US | disclosed |
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9944659-B2 | Boron-containing diacylhydrazine compounds | INTREXON CORPORATION (US) | 2018-04-17 | — | — | US | disclosed |
| US-20180079759-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2018-03-22 | — | — | US | disclosed |
| EP-3194359-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | Intrexon Corporation (US) | 2017-07-26 | — | — | EP | disclosed |
| US-9512148-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| WO-2016044390-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORPORATION (US) | 2016-03-24 | — | — | WO | disclosed |
| US-20160083403-A1 | Boron-Containing Diacylhydrazine Compounds | INTREXON CORPORATION | 2016-03-24 | — | — | US | disclosed |
| EP-2970106-A1 | BORON-CONTAINING DIACYLHYDRAZINES | Intrexon Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127024-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2014144380-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140274954-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083403-A1 | Boron-Containing Diacylhydrazine Compounds | BRDT, CD22, BCR | ABCB1 279/4885CYP3A4 3536/4885TPMT 4166/4885 |
| US-10464951-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
| US-20180201628-A1 | Boron-Containing Diacylhydrazine Compounds | BRDT, CD22, BCR | ABCB1 279/4885CYP3A4 3536/4885TPMT 4166/4885 |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
| US-10851119-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
| US-20140274954-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
| US-10570158-B2 | Boron-containing diacylhydrazine compounds | BRDT, CD22, BCR | ABCB1 279/4885CYP3A4 3536/4885TPMT 4166/4885 |
| US-20180079759-A1 | Boron-Containing Diacylhydrazines | CD22, BRDT, BCR | ABCB1 464/4885CYP3A4 3689/4885TPMT 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.