Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254626 | 0.83 | ABCB1 (0.38) | ABCB1CYP3A4 | |
| SCHEMBL16036638 | 0.83 | ABCB1 (0.40) | ABCB1CYP3A4HTTNPSR1TPMT | |
| SCHEMBL16036634 | 0.83 | ABCB1 (0.40) | ABCB1CYP3A4HTTNPSR1TPMT | |
| SCHEMBL2682853 | 0.74 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL16035449 | 0.74 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL2682569 | 0.74 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL10721628 | 0.74 | ABCB1 (0.53) | ABCB1CYP3A4 | |
| SCHEMBL20052551 | 0.74 | ABCB1 (0.41) | ABCB1CYP3A4 | |
| SCHEMBL28000730 | 0.74 | ABCB1 (0.43) | ABCB1CYP3A4HTT | |
| SCHEMBL28000727 | 0.74 | ABCB1 (0.43) | ABCB1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |