SCHEMBL16038142

SCHEMBL16038142

N#CCCCC#N.N#CCCCC#N

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
TDP1 Q9NUW8 1/20 0.64
TSHR P16473 3/20 0.60
LOX P28300 1/20 0.47
LOXL3 P58215 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.37
NLRP3 Q96P20 1/20 0.35
LCK P06239 1/20 0.35
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60384 1.00
SCHEMBL5319905 0.95 ALDH1A1 (0.58) ALDH1A1TDP1TSHRLOXLOXL3
Lithium SCHEMBL32665726 0.95
Charcoal, Activated SCHEMBL31210106 0.95
SCHEMBL18322220 0.95 ALDH1A1 (0.73) ALDH1A1TDP1TSHRLOXLOXL3
SCHEMBL30678315 0.90
SCHEMBL6000672 0.90 ALDH1A1 (0.64) ALDH1A1TDP1TSHRLOXLOXL3
SCHEMBL59340 0.90
Benzene SCHEMBL28151553 0.88 TSHR (0.50) ALDH1A1TDP1TSHRLOXLOXL3
Cyclohexane SCHEMBL28248940 0.88 TSHR (0.50) ALDH1A1TDP1TSHRLOXLOXL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447213-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140275403-A1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2014-09-18 US disclosed