Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666440 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4663085 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4663133 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL16038174 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL16036952 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL16037164 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL16037420 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4664635 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL16038019 | 1.00 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4662873 | 0.98 | LMNA (0.34) | TSHRTHRBSPHK2SPHK1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284392-B2 | Mixed internal donor structures for 1-olefin polymerization catalysts | BASF CORPORATION (US) | 2016-03-15 | — | — | US | claimed |
| US-20140275452-A1 | MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS | BASF CATALYSTS LLC (US) | 2014-09-18 | — | — | US | claimed |
| CN-110023351-B | Main catalyst composition prepared by combining internal electron donors | 格雷斯公司 | 2022-04-26 | — | — | CN | disclosed |
| US-11014995-B2 | Procatalyst composition made with a combination of internal electron donors | W.R. Grace & Co.—Conn. (US) | 2021-05-25 | — | — | US | disclosed |
| EP-3523343-A1 | PROCATALYST COMPOSITION MADE WITH A COMBINATION OF INTERNAL ELECTRON DONORS | W.R. Grace & Co.-Conn. (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20190211118-A1 | PROCATALYST COMPOSITION MADE WITH A COMBINATION OF INTERNAL ELECTRON DONORS | W. R. GRACE & CO.-CONN. | 2019-07-11 | — | — | US | disclosed |
| WO-2018067367-A1 | PROCATALYST COMPOSITION MADE WITH A COMBINATION OF INTERNAL ELECTRON DONORS | W.R. GRACE & CO.-CONN. (US) | 2018-04-12 | — | — | WO | disclosed |
| US-9284392-B2 | Mixed internal donor structures for 1-olefin polymerization catalysts | BASF CORPORATION (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140275452-A1 | MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS | BASF CATALYSTS LLC (US) | 2014-09-18 | — | — | US | disclosed |