Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898791 | 0.82 | OPRM1 (0.45) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL29116551 | 0.81 | OPRM1 (0.43) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL28209084 | 0.81 | OPRM1 (0.43) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL4423149 | 0.80 | — | — | |
| SCHEMBL29523549 | 0.80 | PLA2G1B (0.46) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL722582 | 0.80 | PLA2G1B (0.46) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL22788446 | 0.79 | — | — | |
| SCHEMBL4652978 | 0.76 | — | — | |
| SCHEMBL28231469 | 0.76 | OPRM1 (0.37) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 | |
| SCHEMBL2547793 | 0.76 | OPRM1 (0.46) | OPRM1PLA2G1BPLA2G2ATP53S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9530571-B2 | Compound and support material supporting this novel compound | ADEKA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| EP-2781555-A1 | NOVEL COMPOUND AND SUPPORT SUPPORTING THIS NOVEL COMPOUND | Adeka Corporation (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-20140261647-A1 | NOVEL COMPOUND AND SUPPORT MATERIAL SUPPORTING THIS NOVEL COMPOUND | ADEKA CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |