Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039961 | 1.00 | ACE (0.45) | ACEITGB3ITGA2BNTSR2NTSR1 | |
| SCHEMBL14486494 | 1.00 | ACE (0.45) | ACEITGB3ITGA2BNTSR2NTSR1 | |
| SCHEMBL14486485 | 1.00 | ACE (0.45) | ACEITGB3ITGA2BNTSR2NTSR1 | |
| SCHEMBL14485988 | 0.96 | ACE (0.48) | ACEITGB3ITGA2BNTSR2NTSR1 | |
| SCHEMBL14485983 | 0.96 | ACE (0.48) | ACEITGB3ITGA2BNTSR2NTSR1 | |
| SCHEMBL29588517 | 0.87 | ACE (0.52) | ACEREN | |
| SCHEMBL29802042 | 0.87 | ACE (0.48) | ACEREN | |
| SCHEMBL29801692 | 0.86 | ACE (0.48) | ACEREN | |
| SCHEMBL29607893 | 0.85 | KDM1A (0.48) | ACEREN | |
| SCHEMBL29801844 | 0.85 | ACE (0.47) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275532-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275532-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | ACE 826/4885ITGB3 3244/4885ITGA2B 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.