Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539971 | 0.83 | MAPT (0.76) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL5539965 | 0.83 | MAPT (0.59) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL3313011 | 0.82 | MAPT (0.58) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL1459682 | 0.82 | MAPT (0.57) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31540771 | 0.81 | MAPT (0.57) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL28072006 | 0.80 | MAPT (0.56) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL5138088 | 0.80 | MAPT (0.56) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL5541814 | 0.80 | MAPT (0.74) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL5541807 | 0.80 | MAPT (0.58) | MAPTLMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL30045088 | 0.79 | MAPT (0.54) | MAPTLMNAGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |