Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoyl Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.53 |
| ▸ | CES1 | P23141 | 9/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1786124 | 0.91 | TSHR (0.61) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16045776 | 0.87 | CES2 (0.59) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16045929 | 0.84 | CES2 (0.55) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL2161015 | 0.84 | TSHR (0.52) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16044283 | 0.82 | CES2 (0.76) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16044455 | 0.82 | CES2 (0.53) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16045181 | 0.82 | CES2 (0.53) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16046639 | 0.82 | CES2 (0.53) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL16044551 | 0.82 | NPSR1 (0.40) | CES2CES1TSHRDAONAPRT | |
| Benzoyl Formic Acid SCHEMBL16045955 | 0.81 | CES2 (0.52) | CES2CES1TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180843-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2022-03-01 | — | — | CN | claimed |
| EP-2969201-B1 | NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS | FORMOSA PLASTICS CORP USA (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-109180843-B | Non-phthalate compounds as electron donors for polyolefin catalysts | 美国台塑公司 | 2022-03-01 | — | — | CN | disclosed |
| US-9790291-B2 | Non-phthalate compounds as electron donors for polyolefin catalysts | FORMOSA PLASTICS CORPORATION, USA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140275456-A1 | NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS | FORMOSA PLASTICS CORPORATION, USA (US) | 2014-09-18 | — | — | US | disclosed |