SCHEMBL16046262

SCHEMBL16046262

CCCC(OS(=O)(=O)c1ccccc1)C(C)C(CC)OC(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
PRKCA P17252 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
POLB P06746 1/20 0.36
ATM Q13315 1/20 0.36
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16046812 0.96 LMNA (0.40) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL16046260 0.95 LMNA (0.39) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL16047777 0.92 TSHR (0.41) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL1783061 0.87 LMNA (0.47) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL16046059 0.85 SMN1; SMN2 (0.47) SMN1; SMN2TSHRALDH1A1CYP1A2ATM
SCHEMBL16048826 0.85 SMN1; SMN2 (0.50) SMN1; SMN2TSHRALDH1A1CYP1A2ATM
SCHEMBL31147024 0.82 TSHR (0.47) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL1786404 0.82 LMNA (0.51) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL1786485 0.82 TSHR (0.53) LMNASMN1; SMN2KMT2AMEN1TP53
SCHEMBL14690196 0.82 TSHR (0.53) LMNASMN1; SMN2KMT2AMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
US-20140275456-A1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-09-18 US disclosed