Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 18/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.61 |
| ▸ | BTK | Q06187 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16048242 | 0.88 | CCNT1 (0.77) | CDK9CCNT1BTK | |
| SCHEMBL16052603 | 0.86 | CCNT1 (0.78) | CDK9CCNT1 | |
| SCHEMBL16049004 | 0.84 | CCNT1 (0.77) | CDK9CCNT1BTK | |
| SCHEMBL16048468 | 0.82 | CCNT1 (0.65) | CDK9CCNT1BTK | |
| SCHEMBL16048010 | 0.82 | CCNT1 (0.75) | CDK9CCNT1BTK | |
| SCHEMBL16048861 | 0.82 | CCNT1 (0.69) | CDK9CCNT1 | |
| SCHEMBL16048959 | 0.81 | CCNT1 (0.77) | CDK9CCNT1BTK | |
| SCHEMBL16047801 | 0.79 | CDK9 (0.77) | CDK9CCNT1BTK | |
| SCHEMBL16048679 | 0.79 | CCNT1 (0.77) | CDK9CCNT1 | |
| SCHEMBL16049101 | 0.79 | CCNT1 (0.76) | CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346813-B2 | Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors | ABBVIE INC. (US) | 2016-05-24 | — | — | US | claimed |
| US-20140275004-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | ABBVIE INC. | 2014-09-18 | — | — | US | claimed |
| US-9346813-B2 | Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors | ABBVIE INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140275004-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | ABBVIE INC. | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275004-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | CDK9, CDK19, CDK3 | CDK9 1/4885CCNT1 36/4885BTK 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.