Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10882360 | 0.86 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1538272 | 0.84 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL947039 | 0.83 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31473107 | 0.83 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11348001 | 0.83 | CA1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30520478 | 0.82 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24533851 | 0.81 | CA1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24779506 | 0.81 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24379343 | 0.81 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9489998 | 0.81 | GAA (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388978-A1 | CEREBLON E3 LIGASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-12-08 | — | — | US | disclosed |
| WO-2021041664-A1 | CEREBLON E3 LIGASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |
| EP-2659037-B1 | CARPETS PREPARED FROM YARNS COMPRISING A FLUORINATED POLYESTER BLEND | DU PONT (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2659040-B1 | A FABRIC PREPARED FROM FLUORINATED POLYESTER BLEND YARNS | DU PONT (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2658923-B1 | FLUORINATED POLYESTER BLEND | DU PONT (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2659036-B1 | FIBERS AND YARNS FROM A FLUORINATED POLYESTER BLEND | DU PONT (US) | 2015-07-29 | — | — | EP | disclosed |
| US-9017788-B2 | Carpets prepared from yarns comprising a fluorinated polyester blend | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-28 | — | — | US | disclosed |
| CN-103298883-B | Fluorinated polyester blend | DU PONT | 2015-04-22 | — | — | CN | disclosed |
| US-8889256-B2 | Fabric prepared from fluorinated polyester blend yarns | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| CN-102575029-B | Polyester film with improved oil repellency | E. I. DU PONT DE NEMOURS AND CO. (US) | 2014-10-15 | — | — | CN | disclosed |
| US-20110218317-A1 | POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218319-A1 | POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218316-A1 | POLYESTER FILMS WITH IMPROVED OIL REPELLENCY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110213118-A1 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2011028791-A2 | POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028778-A2 | POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028771-A2 | POLYESTER FILMS WITH IMPROVED OIL REPELLENCY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| CN-1285818-A | Compounds for antemortem diagnosis and in vivo imaging of alzheimer's disease and prevention of amyloid deposition | UNIV PITTSBURGH (US) | 2001-02-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | PFAS, PAH, AFF4 | CA12 4233/4885CA1 4041/4885CA2 4015/4885 |
| US-20220388978-A1 | CEREBLON E3 LIGASE INHIBITORS | CRBN, CUL3, UBE3A | CA12 2410/4885CA1 1462/4885CA2 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.