Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 1.00 |
| ▸ | CA1 | P00915 | 6/20 | 1.00 |
| ▸ | STS | P08842 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamic Acid Cyclohexyl Ester SCHEMBL57447 | 1.00 | CA2 (1.00) | CA2CA1STSCA12CA9 | |
| SCHEMBL6266117 | 1.00 | CA2 (1.00) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL10856455 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL10648300 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL28963283 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL4592739 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL128016 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL1457949 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL3347620 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL38651257 | 0.97 | CA2 (0.95) | CA2CA1STSCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142699-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | Salk Institute for Biological Studies (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170037117-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-02-09 | — | — | US | disclosed |
| WO-2015176017-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-2015161448-A1 | ORNITHINE-CONTAINING OR ASPARTATE-CONTAINING COMPOSITIONS AND THE USES THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2014139469-A1 | ORNITHINE- OR ASPARTATE-CONTAINING COMPOSITIONS AND THE USES THEREOF | WUHAN QR SCIENCE AND TECHNOLOGY DEVELOPMENT CO. (CN) | 2014-09-18 | — | — | WO | disclosed |