SCHEMBL1605356

SCHEMBL1605356

C=CCc1cccc2[nH]ncc12

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 4/20 0.49
AXL P30530 2/20 0.49
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
IDO1 P14902 3/20 0.46
METAP2 P50579 1/20 0.45
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
TDO2 P48775 1/20 0.40
JAK2 O60674 1/20 0.40
JAK1 P23458 1/20 0.40
GLS O94925 2/20 0.39
HSP90AA1 P07900 1/20 0.37
CDK2 P24941 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24654699 0.83 NOS1 (0.49) NOS1AXLPOLBMAPTIDO1
SCHEMBL19920107 0.83 NOS1 (0.49) NOS1AXLPOLBMAPTIDO1
SCHEMBL27663105 0.77 NOS1 (0.50) NOS1AXLPOLBMAPTIDO1
SCHEMBL12272128 0.77 NOS1 (0.53) NOS1AXLPOLBMAPTIDO1
SCHEMBL20458844 0.77 NOS1 (0.53) NOS1AXLPOLBMAPTIDO1
SCHEMBL29455343 0.77 NOS1 (0.58) NOS1AXLIDO1METAP2TDO2
SCHEMBL14840686 0.77 NOS1 (0.58) NOS1AXLIDO1METAP2TDO2
SCHEMBL6377270 0.77 NOS1 (0.58) NOS1AXLPOLBMAPTIDO1
SCHEMBL2633084 0.77 IDO1 (0.55) NOS1AXLIDO1METAP2TDO2
SCHEMBL30614204 0.77 NOS1 (0.53) NOS1AXLPOLBMAPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103194297-B Lubricating oil composition and preparation method thereof SHANGHAI HITECRUN SPECIALTY LUBRICATION TECHNOLOGY CO LTD 2014-07-09 CN claimed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
EP-2880140-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINES SHELL INT RESEARCH (NL) 2023-03-08 EP disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-20040053794-A1 Lubricating oil composition SHELL OIL COMPANY 2004-03-18 US disclosed
EP-1385926-A1 LUBRICATING OIL COMPOSITION COMPRISING AN ADDITIVE COMBINATION OF A CARBOXYLIC ACID AND AN AMINE AS ANT-RUST AGENT SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2004-02-04 EP disclosed
EP-1354023-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2003-10-22 EP disclosed
WO-2002092735-A1 LUBRICATING OIL COMPOSITION COMPRISING AN ADDITIVE COMBINATION OF A CARBOXYLIC ACID AND AN AMINE AS ANT-RUST AGENT SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-11-21 WO disclosed
WO-2002079358-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-10-10 WO disclosed
EP-1109882-B1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INT RESEARCH (NL) 2002-07-17 EP disclosed
WO-2002053687-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-07-11 WO disclosed
CN-1319126-A Lubricating composition useful in hydraulic fluids SHELL INT RESEARCH (NL) 2001-10-24 CN disclosed
EP-1109882-A1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2001-06-27 EP disclosed
WO-2000011122-A1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2000-03-02 WO disclosed