Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 16/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.51 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.51 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 14/20 | 0.45 |
| ▸ | ATR | Q13535 | 8/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054954 | 0.90 | MTOR (0.49) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055704 | 0.88 | MTOR (0.48) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054160 | 0.79 | MTOR (0.46) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054046 | 0.78 | MTOR (0.66) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055759 | 0.77 | MTOR (0.53) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054292 | 0.77 | MTOR (0.62) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055073 | 0.76 | MTOR (0.51) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055111 | 0.75 | MTOR (0.51) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055563 | 0.75 | MTOR (0.51) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054324 | 0.75 | MTOR (0.52) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014141118-A1 | IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-09-18 | — | — | WO | claimed |
| WO-2014141118-A1 | IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-09-18 | — | — | WO | disclosed |