Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 16/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.49 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | FECH | P22830 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.46 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.46 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.46 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 10/20 | 0.44 |
| ▸ | ATR | Q13535 | 6/20 | 0.44 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054064 | 0.90 | MTOR (0.51) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055759 | 0.88 | MTOR (0.53) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054160 | 0.88 | MTOR (0.46) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055563 | 0.86 | MTOR (0.51) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055097 | 0.82 | MTOR (0.50) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054623 | 0.81 | MTOR (0.48) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16054172 | 0.80 | MTOR (0.45) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055207 | 0.80 | MTOR (0.46) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL16055723 | 0.79 | MTOR (0.44) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905281 | 0.79 | PIK3CA (0.52) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014141118-A1 | IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-09-18 | — | — | WO | disclosed |