Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066556 | 0.85 | TDP1 (0.50) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL18244067 | 0.80 | TDP1 (0.54) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL246480 | 0.76 | TDP1 (0.46) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL249814 | 0.76 | TDP1 (0.46) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL15066089 | 0.71 | TDP1 (0.41) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL16054819 | 0.71 | TDP1 (0.41) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL9412002 | 0.70 | MAPT (0.43) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL9412000 | 0.70 | MAPT (0.43) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL9412005 | 0.70 | MAPT (0.43) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL10321775 | 0.69 | TDP1 (0.50) | TDP1GABRA1GABRG2GABRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968213-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING A MOVEMENT DISORDER | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | claimed |
| EP-2968212-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | claimed |
| WO-2014142520-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | claimed |
| WO-2014142518-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING A MOVEMENT DISORDER | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | claimed |
| EP-2968213-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING A MOVEMENT DISORDER | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014142518-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING A MOVEMENT DISORDER | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |