Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412000 | 1.00 | MAPT (0.43) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9412005 | 1.00 | MAPT (0.43) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10321775 | 0.77 | TDP1 (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3433690 | 0.77 | TDP1 (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9412031 | 0.75 | MAOA (0.51) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9412032 | 0.75 | MAOA (0.51) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9854147 | 0.74 | CYP3A4 (0.44) | MAPTALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL10735723 | 0.73 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10735725 | 0.73 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10735726 | 0.73 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611759-A1 | Pyrimidinyloxy/triazinyloxy alkanol derivatives and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-08-24 | — | — | EP | disclosed |