SCHEMBL16055253

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	1/20	0.49

▸	VIPR2	P41587	7/20	0.48

▸	VIPR1	P32241	6/20	0.48

▸	ENPEP	Q07075	5/20	0.48

▸	NPY1R	P25929	1/20	0.42

▸	NPY2R	P49146	1/20	0.42

▸	NPY4R	P50391	1/20	0.42

▸	NPY5R	Q15761	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30182861	0.95	VIPR2 (0.54)	VIPR2VIPR1NPY1RNPY2RNPY4R
SCHEMBL30182744	0.90	VIPR2 (0.51)	VIPR2VIPR1NPY1RNPY2RNPY4R
SCHEMBL31307261	0.90	RXFP1 (0.47)	VIPR2VIPR1ENPEPNPY1RNPY2R
SCHEMBL30010630	0.90	ENPEP (0.52)	BACE1VIPR1ENPEP
SCHEMBL30011126	0.90	ENPEP (0.52)	BACE1VIPR1ENPEP
SCHEMBL30183026	0.89	VIPR2 (0.55)	BACE1VIPR2VIPR1
SCHEMBL30118952	0.88	RXFP1 (0.49)	BACE1VIPR2VIPR1ENPEP
SCHEMBL30183030	0.87	VIPR2 (0.54)	BACE1VIPR2VIPR1
SCHEMBL29786674	0.87	ENPEP (0.44)	BACE1VIPR2VIPR1ENPEP
SCHEMBL30951004	0.86	ENPEP (0.43)	BACE1VIPR2VIPR1ENPEPNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20180095076-A1	Linked Peptide Fluorogenic Biosensors	CARNEGIE MELLON UNIVERSITY	2018-04-05	—	—	US	disclosed
EP-2972355-A1	LINKED PEPTIDE FLUOROGENIC BIOSENSORS	Carnegie Mellon University (US)	2016-01-20	—	—	EP	disclosed
WO-2014142955-A1	LINKED PEPTIDE FLUOROGENIC BIOSENSORS	CARNEGIE MELLON UNIVERSITY (US)	2014-09-18	—	—	WO	disclosed