SCHEMBL16055575

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	4/20	0.48

▸	OPRL1	P41146	3/20	0.47

▸	GLP1R	P43220	1/20	0.46

▸	GCGR	P47871	1/20	0.46

▸	GIPR	P48546	1/20	0.46

▸	TFPI	P10646	1/20	0.46

▸	RAMP3	O60896	4/20	0.46

▸	CALCR	P30988	4/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31319519	0.93	OPRM1 (0.46)	RXFP1OPRL1GLP1RGCGRGIPR
SCHEMBL9058977	0.91	GLP1R (0.52)	RXFP1OPRL1GLP1RGCGRGIPR
SCHEMBL9058969	0.91	GLP1R (0.52)	RXFP1OPRL1GLP1RGCGRGIPR
SCHEMBL30432774	0.91	OPRL1 (0.53)	RXFP1OPRL1
SCHEMBL29901564	0.89	BACE1 (0.49)	RXFP1GLP1RGCGRGIPRTFPI
SCHEMBL29808495	0.89	NPY4R (0.51)	TFPI
SCHEMBL29625292	0.89	OPRL1 (0.50)	RXFP1OPRL1TFPIRAMP3CALCR
SCHEMBL29975750	0.87	NPY4R (0.53)	—
SCHEMBL30356958	0.87	RXFP1 (0.50)	RXFP1GLP1RGCGRGIPRTFPI
SCHEMBL30356857	0.87	RXFP1 (0.50)	RXFP1GLP1RGCGRGIPRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2972355-A1	LINKED PEPTIDE FLUOROGENIC BIOSENSORS	Carnegie Mellon University (US)	2016-01-20	—	—	EP	disclosed
WO-2014142955-A1	LINKED PEPTIDE FLUOROGENIC BIOSENSORS	CARNEGIE MELLON UNIVERSITY (US)	2014-09-18	—	—	WO	disclosed