SCHEMBL160602

SCHEMBL160602

COc1cccc(OC)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.47
POLB P06746 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.43
KDR P35968 1/20 0.43
CA4 P22748 1/20 0.43
KDM1A O60341 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALOX5 P09917 2/20 0.42
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
GRM5 P41594 1/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3155981 0.86 BTK (0.61) BTKKDM4EALDH1A1HPGDKDR
SCHEMBL29687348 0.84
SCHEMBL29427033 0.84
SCHEMBL128705 0.84
SCHEMBL6964 0.84
SCHEMBL12093509 0.83 GRM5 (0.50) BTKALDH1A1KDRKDM1AMAOA
SCHEMBL12093710 0.83 KDR (0.43) BTKPOLBTDP1KDRGRM5
SCHEMBL1763356 0.82
SCHEMBL4631208 0.82
SCHEMBL128704 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217072-A1 HIGH DART IMPACT AND TEAR FILMS FROM TITANIUM BASED PREPOLYMER CATALYZED POLYETHYLENES FORMOSA PLASTICS CORPORATION, USA (US) 2025-10-16 WO claimed
CN-116396209-B Alkyl perfluoroalkyl ketone compound and preparation method thereof 南方科技大学 2025-04-29 CN claimed
CN-116082237-B Nitrogen-containing heterocyclic compound and preparation method thereof 安徽中医药大学 2025-04-22 CN claimed
CN-117903027-A Method for synthesizing asymmetric disulfide compound by photoinduction catalysis 重庆医科大学 2024-04-19 CN claimed
CN-116396209-A Alkyl perfluoroalkyl ketone compound and preparation method thereof 南方科技大学 2023-07-07 CN claimed
CN-116082237-A Nitrogen-containing heterocyclic compound and preparation method thereof 安徽中医药大学 2023-05-09 CN claimed
CN-112573978-B High-efficiency halogenation synthesis method of aryl halide 北京大学 2022-05-13 CN claimed
CN-112573978-A High-efficiency halogenation synthesis method of aryl halide 北京大学 2021-03-30 CN claimed
US-10772874-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. 2020-09-15 US claimed
US-10456382-B2 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC (US) 2019-10-29 US claimed
WO-2008027479-A2 HIGHLY ACTIVE ALPHA-OLEFIN COPOLYMERIZATION CATALYST SYSTEM FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2008-03-06 WO claimed
EP-1268436-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2003-01-02 EP claimed
WO-2002072556-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-09-19 WO claimed
US-5922206-A Process for treating water for removal of oil and water-soluble petroleum oil components AMCOL INTERNATIONAL CORPORATION (US) 1999-07-13 US claimed
EP-0901805-A1 Process for treating water for removal of oil and water-soluble petroleum oil components AMCOL INTERNATIONAL CORPORATION (US) 1999-03-17 EP claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0460128-B1 AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR Wella Aktiengesellschaft (DE) 1993-06-09 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-4830846-A SALT FORMATION AND NEUTRALIZATION THE DOW CHEMICAL COMPANY (US) 1989-05-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10772874-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 BTK 4176/4885POLB 1931/4885TDP1 3665/4885
US-10456382-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 BTK 4176/4885POLB 1931/4885TDP1 3665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.