Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | DTYMK | P23919 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024450 | 0.81 | TSHR (0.46) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL10024500 | 0.79 | TP53 (0.43) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL10024498 | 0.77 | PDE7A (0.42) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9498874 | 0.75 | ALDH1A1 (0.46) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL21802326 | 0.74 | TSHR (0.47) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL1043222 | 0.74 | POLB (0.57) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL30534229 | 0.74 | POLB (0.57) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL4904 | 0.74 | POLB (0.57) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL27830765 | 0.74 | TSHR (0.50) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL1533771 | 0.71 | TSHR (0.44) | MAPTKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732382-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150079603-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-03-19 | — | — | US | disclosed |
| US-8834847-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-09-16 | — | — | US | disclosed |