Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16603083 | 0.85 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL21241093 | 0.85 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL14431153 | 0.82 | MAPT (0.58) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL23095433 | 0.78 | MAPT (0.54) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL1104624 | 0.78 | MAPT (0.58) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL19336218 | 0.78 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL11785702 | 0.75 | MAPT (0.50) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL11785699 | 0.75 | MAPT (0.50) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL13063848 | 0.73 | MAPT (0.44) | MAPTALDH1A1HTTSMN1; SMN2HIF1A | |
| SCHEMBL19336216 | 0.72 | MAPT (0.52) | MAPTALDH1A1HTTSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144673-A1 | PHOTOACTIVE ADDITIVES CONTAINING SILOXANE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-09-18 | — | — | WO | disclosed |