SCHEMBL16065804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17465858	0.87	NUAK1 (0.67)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL16065850	0.85	LRRK2 (0.65)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL16065849	0.81	NUAK1 (1.00)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL618577	0.79	LRRK2 (1.00)	LRRK2MAPK7DCLK1BRD4BRDT
	SCHEMBL30797848	0.79	DCLK1 (1.00)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL10098752	0.79	DCLK1 (1.00)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL10098750	0.78	NUAK1 (0.79)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL16140987	0.78	NUAK1 (0.68)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL619716	0.77	NUAK1 (0.95)	NUAK1LRRK2MAPK7DCLK1BRD4
	SCHEMBL616339	0.77	MAPK7 (1.00)	NUAK1LRRK2MAPK7DCLK1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.