SCHEMBL16066976

SCHEMBL16066976

Fc1cccc(-c2cc(-c3cccc(F)c3)nc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3c3nc4ccccc4n53)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HPGD P15428 4/20 0.39
KMT2A Q03164 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 6/20 0.38
MAPT P10636 3/20 0.34
ADORA2A P29274 2/20 0.34
POLB P06746 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TP53 P04637 2/20 0.34
LMNA P02545 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
XBP1 P17861 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
EGFR P00533 1/20 0.33
ACP1 P24666 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067126 0.97 ALDH1A1 (0.39) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066779 0.91 KDM4E (0.43) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL17033664 0.90 ALDH1A1 (0.35) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066196 0.88 ALDH1A1 (0.39) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066543 0.88 KDM4E (0.42) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066693 0.88 KDM4E (0.45) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066958 0.87 ALDH1A1 (0.39) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL16066954 0.87 KDM4E (0.44) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E
SCHEMBL17033510 0.86 KDM4E (0.35) ALDH1A1KMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL16066604 0.86 ALDH1A1 (0.38) ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 WO disclosed