Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585894 | 1.00 | TRPA1 (0.53) | TRPA1TDP1LMNAIDO1LOXL2 | |
| SCHEMBL29913385 | 0.91 | ESR1 (0.45) | TRPA1LMNAESR1ESR2 | |
| SCHEMBL13849892 | 0.85 | TRPA1 (0.48) | TRPA1TDP1LMNAIDO1LOXL2 | |
| SCHEMBL14402399 | 0.85 | TRPA1 (0.48) | TRPA1TDP1LMNAIDO1LOXL2 | |
| SCHEMBL23347526 | 0.82 | TRPA1 (0.46) | TRPA1TDP1 | |
| SCHEMBL14402605 | 0.82 | TRPA1 (0.46) | TRPA1TDP1 | |
| SCHEMBL18779904 | 0.82 | GRIN2D (0.41) | TRPA1IDO1PPARGPPARAESR1 | |
| SCHEMBL14402400 | 0.82 | GRIN2D (0.41) | TRPA1IDO1PPARGPPARAESR1 | |
| SCHEMBL106892 | 0.82 | ESR1 (0.59) | TDP1LMNAESR1ESR2 | |
| SCHEMBL26238707 | 0.82 | GRIN2D (0.41) | TRPA1IDO1PPARGPPARAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968211-B1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO PHARM SOLUTIONS CO LTD (KR) | 2021-05-12 | — | — | EP | disclosed |
| WO-2014142519-A1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |