⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806259 | 0.72 | — | — | |
| SCHEMBL8123470 | 0.72 | — | — | |
| SCHEMBL12497498 | 0.70 | — | — | |
| SCHEMBL15056481 | 0.68 | — | — | |
| SCHEMBL2853843 | 0.68 | — | — | |
| SCHEMBL4455224 | 0.67 | — | — | |
| SCHEMBL3617785 | 0.66 | — | — | |
| SCHEMBL7102621 | 0.65 | — | — | |
| SCHEMBL18131671 | 0.64 | — | — | |
| SCHEMBL9503371 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557971-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2015-06-17 | — | — | CN | claimed |
| US-8841296-B2 | Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof | Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg (IN) | 2014-09-23 | — | — | US | claimed |
| CN-102796050-B | Cdc42 inhibitor and application thereof | ANGKE BIOLOG MEDICLA TECHNOLOGY SUZHOU CO LTD | 2014-07-23 | — | — | CN | claimed |
| CN-110526907-A | Benzoxazine ketones derivant and its application | UNIV SICHUAN | 2019-12-03 | — | — | CN | disclosed |
| CN-110291652-A | Organic electroluminescent element | 学校法人关西学院 | 2019-09-27 | — | — | CN | disclosed |
| CN-110249442-A | Organic electroluminescent element | 学校法人关西学院 | 2019-09-17 | — | — | CN | disclosed |
| CN-106458994-B | Biaryl kinase inhibitor | 百时美施贵宝公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-105330646-B | A kind of preparation method of antineoplastic maleic acid linatinib | 上海勋和医药科技有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105164142-B | Mannose Derivatives for the Treatment of Bacterial Infections | 沃泰克斯药物股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-103242192-B | The inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 type enzyme | ABBVIE INC. (US) | 2016-05-04 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |
| CN-105384739-A | Pyrazolo[3,4-c]pyridine derivative | CSPC ZHONGQI PHARMACEUTICAL TECH (SHIJIAZHUANG) CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-105330646-A | Preparation method of antineoplastic drug maleic acid neratinib | SHANGHAI XUNHE PHARMACEUTICAL TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |
| CN-105164142-A | Mannose derivatives for the treatment of bacterial infections | VERTEX PHARMA | 2015-12-16 | — | — | CN | disclosed |
| CN-102884047-B | 2-pyridone compounds | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-103025721-B | Picolinamide and pyrimidine-4-carboxamide compounds, process for preparing and pharmaceutical composition comprising the same | SK CHEMICALS CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102557971-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2015-06-17 | — | — | CN | disclosed |
| CN-103998429-A | Substituted anilines as ccr(4) antagonists | CHEMOCENTRYX INC | 2014-08-20 | — | — | CN | disclosed |
| CN-102796050-B | Cdc42 inhibitor and application thereof | ANGKE BIOLOG MEDICLA TECHNOLOGY SUZHOU CO LTD | 2014-07-23 | — | — | CN | disclosed |