Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 7/20 | 0.36 |
| ▸ | ENO1 | P06733 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16069985 | 1.00 | NR4A1 (0.51) | NR4A1NR4A2NR4A3ALDH1A1BTN3A1 | |
| SCHEMBL16069987 | 1.00 | NR4A1 (0.51) | NR4A1NR4A2NR4A3ALDH1A1BTN3A1 | |
| SCHEMBL22525396 | 0.90 | ALDH1A1 (0.42) | NR4A1NR4A2NR4A3ALDH1A1BTN3A1 | |
| SCHEMBL22526263 | 0.86 | ALDH1A1 (0.43) | NR4A1NR4A2NR4A3ALDH1A1BTN3A1 | |
| SCHEMBL16069970 | 0.83 | NR4A1 (0.58) | NR4A1NR4A2NR4A3ALDH1A1TBXAS1 | |
| SCHEMBL16069969 | 0.83 | NR4A1 (0.58) | NR4A1NR4A2NR4A3ALDH1A1TBXAS1 | |
| SCHEMBL16069992 | 0.83 | NR4A1 (0.58) | NR4A1NR4A2NR4A3ALDH1A1TBXAS1 | |
| SCHEMBL16070080 | 0.81 | NR4A1 (0.45) | NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL16070083 | 0.81 | NR4A1 (0.45) | NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL16070082 | 0.81 | NR4A1 (0.45) | NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |