Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16069991 | 1.00 | CYP3A4 (0.43) | CYP3A4POLBTDP1CTDSP1MEN1 | |
| SCHEMBL16069988 | 1.00 | CYP3A4 (0.43) | CYP3A4POLBTDP1CTDSP1MEN1 | |
| SCHEMBL556708 | 0.87 | KMT2A (0.39) | CYP3A4POLBTDP1CTDSP1MEN1 | |
| SCHEMBL16069990 | 0.85 | KDM4E (0.42) | POLBTDP1NR4A1NR4A2NR4A3 | |
| SCHEMBL556710 | 0.75 | RXFP2 (0.36) | CYP3A4POLBTDP1CTDSP1NPC1 | |
| SCHEMBL16069992 | 0.74 | NR4A1 (0.58) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL16069969 | 0.74 | NR4A1 (0.58) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL16069970 | 0.74 | NR4A1 (0.58) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL556709 | 0.73 | TSHR (0.38) | POLBSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL16069987 | 0.72 | NR4A1 (0.51) | NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |