Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16070000 | 1.00 | NR4A1 (0.51) | NR4A1NR4A2NR4A3TBXAS1ESR1 | |
| SCHEMBL557076 | 1.00 | NR4A1 (0.51) | NR4A1NR4A2NR4A3TBXAS1ESR1 | |
| SCHEMBL6655426 | 0.80 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPTALDH1A1 | |
| SCHEMBL6655419 | 0.80 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPTALDH1A1 | |
| SCHEMBL6655424 | 0.80 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPTALDH1A1 | |
| SCHEMBL9820463 | 0.79 | ELANE (0.59) | NR4A1NR4A2NR4A3TBXAS1ESR1 | |
| Hydrochloric Acid SCHEMBL9445571 | 0.79 | CA1 (0.57) | NR4A1NR4A2NR4A3MAPTALDH1A1 | |
| SCHEMBL557075 | 0.78 | BLM (0.51) | NR4A1NR4A2NR4A3TBXAS1ESR1 | |
| SCHEMBL28297767 | 0.77 | MAPT (0.61) | MAPTHPGDRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9820527 | 0.77 | ELANE (0.58) | NR4A1NR4A2NR4A3TBXAS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |