⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20259577 | 1.00 | — | — | |
| SCHEMBL17414095 | 0.65 | — | — | |
| SCHEMBL20259610 | 0.65 | — | — | |
| SCHEMBL16070113 | 0.65 | — | — | |
| SCHEMBL16070118 | 0.64 | — | — | |
| SCHEMBL16070441 | 0.63 | — | — | |
| SCHEMBL17414093 | 0.63 | — | — | |
| SCHEMBL20259611 | 0.63 | — | — | |
| SCHEMBL9707294 | 0.62 | ALOX15 (0.33) | — | |
| SCHEMBL20094562 | 0.58 | CYP19A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162897-A1 | TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | UNIVERSITAET BERN (CH) | 2018-06-14 | — | — | US | disclosed |
| US-9862742-B2 | Tricyclic nucleosides and oligomeric compounds prepared therefrom | Universität Bern (CH) | 2018-01-09 | — | — | US | disclosed |
| US-20160002280-A1 | TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | UNIVERSITAT BERN (CH) | 2016-01-07 | — | — | US | disclosed |
| US-20160002280-A1 | TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | UNIVERSITAT BERN (CH) | 2016-01-07 | — | — | US | disclosed |
| WO-2014140348-A1 | TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | Universität Bern (CH) | 2014-09-18 | — | — | WO | disclosed |