Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 14/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16070188 | 0.85 | FGFR4 (0.43) | FGFR4PTK2FGFR1FGFR2FGFR3 | |
| SCHEMBL16069924 | 0.82 | FGFR4 (0.44) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16070359 | 0.81 | FGFR1 (0.49) | FGFR4PTK2FGFR1 | |
| SCHEMBL19101498 | 0.81 | IGF1R (0.45) | FGFR4PTK2 | |
| SCHEMBL16050076 | 0.81 | FGFR1 (0.49) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL17469985 | 0.81 | PTK2 (0.45) | FGFR4PTK2FGFR1FGFR2FGFR3 | |
| SCHEMBL16069925 | 0.80 | FGFR3 (0.47) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16070501 | 0.80 | FGFR4 (0.45) | FGFR4PTK2FGFR1FGFR2FGFR3 | |
| SCHEMBL16070505 | 0.80 | FGFR3 (0.52) | FGFR4FGFR1FGFR3 | |
| SCHEMBL16070227 | 0.80 | FGFR3 (0.60) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139465-A1 | NOVEL PYRIMIDINE AND PYRIDINE COMPOUNDS AND THEIR USAGE | HUTCHISON MEDIPHARMA LIMITED (CN) | 2014-09-18 | — | — | WO | disclosed |