SCHEMBL16070566

SCHEMBL16070566

CO[C@@H](C(C)C)[C@@H](O)c1c(C)cccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LCK P06239 1/20 0.31
GAA P10253 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18567965 1.00 TSHR (0.32) TSHRSMN1; SMN2LCKGAAMEN1
SCHEMBL16071183 0.90 TSHR (0.35) TSHRSMN1; SMN2MEN1LMNAKMT2A
SCHEMBL16064837 0.83 TSHR (0.36) TSHRSMN1; SMN2GAAMEN1LMNA
SCHEMBL18568257 0.83 TSHR (0.36) TSHRSMN1; SMN2GAAMEN1LMNA
SCHEMBL19254449 0.80 GAA (0.33) TSHRSMN1; SMN2GAALMNA
SCHEMBL18567607 0.80 GAA (0.33) TSHRSMN1; SMN2GAALMNA
SCHEMBL16071369 0.80 GAA (0.33) TSHRSMN1; SMN2GAALMNA
SCHEMBL16070804 0.79 GAA (0.35) TSHRSMN1; SMN2GAALMNA
SCHEMBL18567950 0.76 KDM4E (0.34) GAAMEN1KMT2A
SCHEMBL16070561 0.76 KDM4E (0.34) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2527314-B1 Process for preparation of phenyl carbamate derivatives BIO-PHARM SOLUTIONS CO LTD (KR) 2017-10-04 EP disclosed
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed
EP-2797880-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY BIO-PHARM SOLUTIONS CO LTD (KR) 2017-03-01 EP disclosed
WO-2014142477-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PEDIATRIC EPILESY AND EPILESY-RELATED SYNDROMES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed
WO-2013100571-A9 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed