SCHEMBL18567950

SCHEMBL18567950

CC[C@@H](OC)[C@H](O)c1c(C)cccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HSD17B10 Q99714 1/20 0.33
CASP1 P29466 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
DRD2 P14416 2/20 0.31
DRD3 P35462 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ITGB1 P05556 1/20 0.31
ITGA4 P13612 1/20 0.31
RORC P51449 1/20 0.30
HTT P42858 2/20 0.30
PYGL P06737 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16070561 1.00 KDM4E (0.34) KDM4EMEN1KMT2AHSD17B10CASP1
SCHEMBL16064847 0.85 MEN1 (0.36) KDM4EMEN1KMT2AHSD17B10TAS1R3
SCHEMBL23347628 0.85 MEN1 (0.36) KDM4EMEN1KMT2AHSD17B10TAS1R3
SCHEMBL18567969 0.85 MEN1 (0.36) KDM4EMEN1KMT2AHSD17B10TAS1R3
SCHEMBL19254451 0.85 MEN1 (0.36) KDM4EMEN1KMT2AHSD17B10TAS1R3
SCHEMBL19254710 0.82 KDM4E (0.35) KDM4EMEN1KMT2AHSD17B10CASP1
SCHEMBL16064906 0.82 KDM4E (0.35) KDM4EMEN1KMT2AHSD17B10CASP1
SCHEMBL16064837 0.79 TSHR (0.36) KDM4EMEN1KMT2AHSD17B10ALDH1A1
SCHEMBL18568257 0.79 TSHR (0.36) KDM4EMEN1KMT2AHSD17B10ALDH1A1
SCHEMBL18567965 0.76 TSHR (0.32) MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2527314-B1 Process for preparation of phenyl carbamate derivatives BIO-PHARM SOLUTIONS CO LTD (KR) 2017-10-04 EP disclosed
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed
EP-2797880-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY BIO-PHARM SOLUTIONS CO LTD (KR) 2017-03-01 EP disclosed