Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055394 | 0.95 | PDE5A (0.46) | PDE5ATOP1CNR1CNR2TP53 | |
| SCHEMBL6055266 | 0.89 | PDE5A (0.40) | PDE5ATP53TDP1TRPA1LMNA | |
| SCHEMBL9082794 | 0.84 | TP53 (0.38) | PDE5ATP53TDP1TRPA1LMNA | |
| SCHEMBL20342536 | 0.81 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL6055146 | 0.81 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL10884999 | 0.81 | PDE5A (0.38) | PDE5ACNR1CNR2TP53TDP1 | |
| SCHEMBL3843495 | 0.80 | PDE5A (0.39) | PDE5ATOP1TP53LMNACHRM1 | |
| SCHEMBL9297557 | 0.80 | PDE5A (0.39) | PDE5ATOP1TP53LMNACHRM1 | |
| SCHEMBL12630806 | 0.80 | SLC6A2 (0.41) | PDE5ATP53TDP1TRPA1LMNA | |
| SCHEMBL23347583 | 0.79 | PDE5A (0.37) | PDE5ACNR1CNR2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142550-A1 | PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR PREVENTING OR TREATING A PSYCHIATRIC DISORDER COMPRISING THE SAME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |