Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055394 | 0.85 | PDE5A (0.46) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL16071368 | 0.84 | PDE5A (0.51) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL6055266 | 0.83 | PDE5A (0.40) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL12630806 | 0.81 | SLC6A2 (0.41) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL4599145 | 0.81 | KMT2A (0.36) | TDP1LMNAMEN1KMT2AHTT | |
| SCHEMBL9081255 | 0.80 | ADRA2A (0.44) | ADRA1AHTT | |
| SCHEMBL6055146 | 0.79 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL14531985 | 0.79 | TP53 (0.41) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL20342536 | 0.79 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL2995079 | 0.77 | KMT2A (0.46) | TP53PDE5AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525736-A | REACTION OF DIOL COMPOUND OR CYCLIC ETHER WITH MERCAPTO COMPOUND AND STRONG PROTONOIC ACID | CIBA-GEIGY CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0570376-A1 | A PROCESS FOR THE PRODUCTION OF CYCLIC SULFONIUM SALTS | Ciba SC Holding AG (CH) | 1993-11-24 | — | — | EP | disclosed |
| WO-1993009112-A1 | A PROCESS FOR THE PRODUCTION OF CYCLIC SULFONIUM SALTS | CIBA-GEIGY AG (CH) | 1993-05-13 | — | — | WO | disclosed |