SCHEMBL16072188

SCHEMBL16072188

CCCC[C@H](O)[C@@H](O)c1ccc(C)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE5A O76074 1/20 0.36
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 2/20 0.33
TRPA1 O75762 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
KMT2A Q03164 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23347585 1.00 MAPT (0.36) MAPTRAB9AATML3MBTL1PDE5A
SCHEMBL29529386 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL29528426 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL253968 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL251303 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL29529394 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL253969 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL253982 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL253983 0.86 LMNA (0.43) MAPTL3MBTL1CNR1CNR2LMNA
SCHEMBL23347583 0.84 PDE5A (0.37) PDE5ACNR1CNR2LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142547-A1 PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR NEUROPROTECTION COMPRISING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed