SCHEMBL16072199

SCHEMBL16072199

CCCCCCCCC1CCC(CCC2CCC(C3CCC(C4CCC(CCCCCC)CC4)C(F)C3F)CC2)C(F)C1F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
EPHX1 P07099 1/20 0.31
LSS P48449 2/20 0.31
PKM P14618 1/20 0.31
ALOX5 P09917 1/20 0.30
GNAO1 P09471 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16072263 1.00 CYP1A2 (0.33) CYP1A2MEN1HTTKMT2ATP53
SCHEMBL16071988 1.00 CYP1A2 (0.33) CYP1A2MEN1HTTKMT2ATP53
SCHEMBL16072197 0.96 CHRNB2 (0.31) CHRNB2CHRNA7CHRNA4EPHX1
SCHEMBL16071982 0.96 CHRNB2 (0.31) CHRNB2CHRNA7CHRNA4EPHX1
SCHEMBL16072221 0.94 CHRNB2 (0.33) CHRNB2CHRNA7CHRNA4
SCHEMBL16071862 0.94 CYP1A2 (0.30) CYP1A2
SCHEMBL16072193 0.94 CYP1A2 (0.33) CYP1A2MEN1HTTKMT2APKM
SCHEMBL16071704 0.93
SCHEMBL16072400 0.91 CYP1A2 (0.33) CYP1A2MEN1HTTKMT2APKM
SCHEMBL17620774 0.91 CYP1A2 (0.33) CYP1A2MEN1HTTKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305627-B1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2014-09-17 EP disclosed