Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23712408 | 0.87 | CHRM1 (0.47) | CHRM1CHRM4TSHRLMNACHRM2 | |
| SCHEMBL6105382 | 0.86 | STS (0.46) | CHRM1CHRM4TSHRLMNACHRM2 | |
| SCHEMBL6105386 | 0.86 | STS (0.46) | CHRM1CHRM4TSHRLMNACHRM2 | |
| SCHEMBL13175813 | 0.81 | CHRM2 (0.54) | CHRM1CHRM4LMNACHRM2CHRM3 | |
| SCHEMBL5790060 | 0.80 | HTR3E (0.63) | CHRM1CHRM4LMNACHRM2CHRM3 | |
| SCHEMBL13698870 | 0.80 | HTR3E (0.63) | CHRM1CHRM4LMNACHRM2CHRM3 | |
| SCHEMBL5791676 | 0.80 | HTR3E (0.63) | CHRM1CHRM4LMNACHRM2CHRM3 | |
| SCHEMBL18589685 | 0.80 | HTR3E (0.63) | CHRM1CHRM4TSHRLMNACHRM2 | |
| SCHEMBL18577676 | 0.80 | HTR3E (0.63) | CHRM1CHRM4TSHRLMNACHRM2 | |
| SCHEMBL18590685 | 0.80 | HTR3E (0.63) | CHRM1CHRM4TSHRLMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014140318-A1 | IMPROVED PROCESS FOR ACYL TRANSFER REACTIONS | K.H.S. PHARMA HOLDING GMBH (DE) | 2014-09-18 | — | — | WO | disclosed |