Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SI | P14410 | 3/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16073053 | 0.88 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL10201673 | 0.84 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL10201677 | 0.84 | NPC1 (0.60) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8797043 | 0.83 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL3196687 | 0.76 | NPC1 (0.62) | GAANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5733209 | 0.75 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL16073076 | 0.75 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL27760115 | 0.75 | NPC1 (0.68) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL419202 | 0.74 | CYP1A2 (0.71) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL16073042 | 0.73 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | STAT1, MLEC, CGAS | MGAM 416/4885GAA 3218/4885SI 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.