Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078325 | 0.90 | MEN1 (0.62) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL16073080 | 0.88 | KDM4E (0.62) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL17132004 | 0.85 | MEN1 (0.54) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL14551103 | 0.82 | NPC1 (0.76) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL22728474 | 0.82 | MAPT (0.59) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL22728480 | 0.81 | MEN1 (0.59) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL2753589 | 0.80 | RAB9A (0.71) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL31135053 | 0.80 | USP2 (0.86) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL235190 | 0.79 | KDM4E (0.70) | MAPK1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL12515352 | 0.79 | RAB9A (0.58) | MAPK1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | STAT1, MLEC, CGAS | MAPK1 156/4885MAPT 4786/4885RAB9A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.