Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | BCR | P11274 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12586702 | 0.87 | CYP3A4 (0.77) | CYP3A4ALDH1A1ACHEHPGDABL1 | |
| SCHEMBL30277943 | 0.85 | CYP3A4 (0.74) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL3300408 | 0.85 | CYP3A4 (0.74) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL14553798 | 0.84 | CYP3A4 (0.71) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL67338 | 0.80 | CYP3A4 (0.67) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL10521152 | 0.80 | CYP3A4 (0.67) | CYP3A4ALDH1A1ACHESMN1; SMN2TDP1 | |
| SCHEMBL12311286 | 0.79 | CYP3A4 (0.63) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL4646583 | 0.78 | TDP1 (0.75) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL10106588 | 0.77 | CYP3A4 (0.62) | CYP3A4ALDH1A1HPGDABL1ABCB1 | |
| SCHEMBL8867887 | 0.77 | GAA (0.62) | CYP3A4ALDH1A1ACHEHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021716-B1 | CONDENSATION PRODUCT AND LITHOGRAPHIC PRINTING PLATES CONTAINING SAID PRODUCT | KONICA CORPORATION (JP) | 1984-02-15 | — | — | EP | claimed |
| US-20180042899-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-15 | — | — | US | disclosed |
| EP-2438078-B1 | NOVOBIOCIN ANALOGUES HAVING MODIFIED SUGAR MOIETIES | UNIV KANSAS (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9120774-B2 | Novobiocin analogues having modified sugar moieties | UNIVERSITY OF KANSAS (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120774-B2 | Novobiocin analogues having modified sugar moieties | UNIVERSITY OF KANSAS (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120774-B2 | Novobiocin analogues having modified sugar moieties | UNIVERSITY OF KANSAS (US) | 2015-09-01 | — | — | US | disclosed |
| US-20140050694-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-20 | — | — | US | disclosed |
| EP-1981889-B1 | CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE | SANOFI SA (FR) | 2014-01-15 | — | — | EP | disclosed |
| US-8313734-B2 | Malodour counteracting composition | FIRMENICH SA (CH) | 2012-11-20 | — | — | US | disclosed |
| US-20120252745-A1 | NOVOBIOCIN ANALOGUES HAVING MODIFIED SUGAR MOIETIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-10-04 | — | — | US | disclosed |
| US-20070042997-A1 | Medicament for treatment of dermal pigmentation | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-02-22 | — | — | US | disclosed |
| US-4770973-A | READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT | Kanzaki Paper Manufacturing Limited (JP) | 1988-09-13 | — | — | US | disclosed |
| US-4575479-A | HIGH SPEED; PHOTO-FIXING ABILITY | RICOH COMPANY, LTD. (JP) | 1986-03-11 | — | — | US | disclosed |
| US-4542394-A | MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND | RICOH COMPANY, LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
| EP-0065720-B1 | PROCESS FOR PREPARING HYDROXYPHENYL AMINE DERIVATIVES | CASSELLA Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |
| US-4477553-A | AN O QUINONEDIAZIDE AND A DIHYDROXYBENZENE-BASED PHENOLIC OR POLYPHENYL RESIN BINDER; LITHOGRAPHIC PRINTING PLATES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4454521-A | PETROLEUM RESIN LAYER | RICOH COMPANY, LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0021716-B1 | CONDENSATION PRODUCT AND LITHOGRAPHIC PRINTING PLATES CONTAINING SAID PRODUCT | KONICA CORPORATION (JP) | 1984-02-15 | — | — | EP | disclosed |
| EP-0065720-A1 | Process for preparing hydroxyphenyl amine derivatives | CASSELLA Aktiengesellschaft (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0054258-A2 | Photosensitive compositions | KONICA CORPORATION (JP) | 1982-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252745-A1 | NOVOBIOCIN ANALOGUES HAVING MODIFIED SUGAR MOIETIES | HSP90AB1, HSP90AB2P, HSP90B1 | CYP3A4 3151/4885ALDH1A1 3066/4885ACHE 4861/4885 |
| US-20070042997-A1 | Medicament for treatment of dermal pigmentation | TYR, XDH, XPA | CYP3A4 2041/4885ALDH1A1 140/4885ACHE 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.